Pay With Bitcoin Get 10% Discount Code : BTC10

Buy Dermal Fillers Online

Plinest Newest (1x2ml)



PLINEST MASTELLI is a series of preparations of the renowned Italian pharmaceutical company Mastelli, which are a mixture of polynucleotides in gel form, and in the case of one preparation, a mixture of polynucleotides and hyaluronic acid (Newest).

The Mastelli company has been present on the medical market for over 60 years, meeting the highest criteria of production systems and safety. Injectables have the CE0373 registration and are protected by the worldwide Mastelli patent for the production of polynucleotides in medicine.

Polynucleotides are fragments of DNA and RNA nucleic acids . Chemically, they are esters of nucleosides and phosphoric acid. Polynucleotides are found in all organisms. Their role is, among other things, to regenerate the skinafter severe injuries and diseases. They are responsible for increasing the firmness, tension and elasticity of the skin (biorevitalization). Their presence helps to regain the aesthetics and functionality of the areas with overgrowths of the fibrous component (stretch marks, scars of dystrophic or regularly damaged areas). They also protect DNA against damage caused by UVA and UVB radiation.

Their regular administration causes prolonged isoosomotic moisturization , improves the trophic conditions of the dermal matrix, and regenerates and stimulates fibroblasts, which directly affects the appearance and condition of the skin .

The entire range of products based on polynucleotides allows for quick regeneration of the skin of the face, neck, hands and décolleté, as well as skin laxity throughout the body.
Designed for patients of all ages. Recommended as one of the most effective treatments used in the prevention of aging.

Thanks to the combination of hyaluronic acid and polynucleotides (which have proven anti-aging prophylaxis) in NEWEST, the effect of the mesotherapy treatment is multiplied .

Hyaluronic acid and polynucleotides mutually reinforce each other’s action :

  • antioxidant protection
  • tissue hydration
  • metabolic regeneration of fibroblasts
  • stimulating fibroblasts to produce collagen and elastin
  • inhibiting photo- and chronaging processes

The NEWEST® formula also contains mannitol.

Mannitol has an oxidative effect, thanks to which it protects the skin against free radicals, and also protects the administered non-cross-linked hyaluronic acid against rapid degradation. It also has the ability to attract water.



  • Uneven skin tone
  • Wrinkles and furrows
  • Tear Valley Correction
  • Laxity and aging of the neck skin
  • Hand skin rejuvenation

  • Face
  • Cleavage
  • Neck
  • Hands
TREATMENT PROGRAM:The effects are visible after the first treatment, because NEWEST is hyaluronic acid and polynucleotides with synergistic enhanced effects. The best results are achieved with a series of 3 treatments every 3 weeks.

To maintain the effect, we recommend a NEWEST mesotherapy reminding treatment every 3 months.

NEWEST is best used systematically throughout the year, with greater intensity in summer (protection of the skin against solar radiation) and in winter.


  • PDNR + HA macromolecules 20 mg per 1 ml 
PACKAGE CONTAINS: 1 syringe with 2 ml of the preparation.

Attention! The product is to be used only by qualified medical personnel.


There are no reviews yet.

Be the first to review “Plinest Newest (1x2ml)”

Your email address will not be published. Required fields are marked *

Select the fields to be shown. Others will be hidden. Drag and drop to rearrange the order.
  • Image
  • SKU
  • Rating
  • Price
  • Stock
  • Availability
  • Add to cart
  • Description
  • Content
  • Weight
  • Dimensions
  • Additional information
Click outside to hide the comparison bar